Research Internship Program :: Past Topics

The following is a list of some past research projects:

Biochemistry

  • PKA-induced phosphorylation of p65 is necessary for NF-kB activation in Schwann cells
  • Crystallization of the cyanobacteria circadian clock protein
  • Inhibition and Analysis of COX-1 and COX-2A in Zebrafish

Biological Sciences

  • MonoUbiqitin mediated Drs2p sorting into the MVB pathway
  • Role of G-proteins in Dictyostelium discoideum slug phototaxis
  • The development of primers to detect sewage pollution in recreational water
  • Investigating the roles of Apelin in zebrafish development by using the Gal4/UAS system

Biomedical Engineering

  • Surface modification of HTR to increase porosity and cell adhesion

Cancer Biology

  • RGS2 Protein Expression in Myeloid Cells in Response to Cell Stress

Cell and Developmental Biology

  • Determining the cytoarchitecture of the left lateral plate mesoderm in Xenopus laevis
  • Genetic analysis of UNC-4 suppressor mutants
  • Diet modulates egg production in dFOXO-independent manner
  • Notch signaling pathway's role in hepatogenesis
  • Phosphorylation interactions of clp1

Center for Human Genetic Research

  • Determining the effects of citrulline on the regulation of urea cycle enzymes and nitric oxide cycle synthases
  • Potential role for PYY in appetite suppression associated with UCD patients
  • Evidence for oxidant injury from hyperoxia during cardiac surgery

Chemical Engineering

  • Polyurethane-mineralized bone powder composites

Chemistry

  • Assessing the capabilities of fragment-independent encoding of drug-like molecules using radial distribution functions and artificial neural networks
  • Novel molecular transporter for the delivery of bioactive cargo
  • Computational de novo folding of the leucine transporter membrane protein

Earth and Environmental Sciences

  • Hydrothermal zircon growth at high pressures and temperatures
  • Testing for the provenance differences in aquifer sands from arsenic infected regions of Nepal using rare earth elements and zircon geochronology
  • The layering of calcium carbonate as it relates to changes in climate

Electrical Engineering and Computer Science

  • Acoustical properties of speech as indicators of depression and suicidal risk
  • Validating a perceptual concept of locus

Hearing and Speech Sciences

  • Preschoolers’ production of complement clauses in an elicited language task

Mechanical Engineering

  • Electro-osmotic pumping flow rate optimization via annealing

Medicine

  • The effect of resveratrol on renal sodium excretion in mice fed with high sodium diet
  • Effect of Rev M10 on SIV RRE-mediated expression of HIV Gag-Pol
  • Effect of Rev M10 on CTE-mediated expression of HIV Gag-Pol
  • The role of MTG8 in intestinal and colonic biology
  • The disruption of embryonic signaling pathways as a result of exposure to small molecule compounds
  • Developing an fMRI capable neck suction device for carotid sinus stimulation
  • Chemotherapy agent enhances citrullination in murine fibrotic lung tissue

Microbiology and Immunology

  • HIV uncoating perturbed by TRIM5α
  • Antimicrobial peptides that inhibit HIV and protect beneficial lactobacilli

Molecular Physiology and Biophysics

  • Analysis of CaMKII signaling complexes in mouse and rat striatum and hippocampus
  • MIP-1α’s role in the inflammatory response to fatty acids
  • Investigation of the endocytic pathway traversed by cholera toxin using fluorescence microscopy and image analysis

Pathology

  • Reactive oxygen species contribute to the tumorigenicity of polyploidy cells
  • Decrease in CCS from dithiocarbamates results from increase in bioavailability of copper in brain

Pediatrics

  • Manganese exposure induces neuronal injury
  • Gfi-1b interacts with the intracellular domain of Notch

Pharmacology

  • Strain-specific postnatal lethality in mutant mice solely expressing the fully-edited isoform of the serotonin 2C receptor
  • D1 and D2 dopamine receptor expression in corticostriatal neurons of the rat
  • MET protein expression in the cortex of uPAR -/- mice
  • Role of dopamine receptors in neuronal development

Physics and Astronomy

  • Calibration of an optical tweezer setup
  • The process of isotropic to anisotropic transformation from the nanocrystal to the nanospindle
  • Germ band retraction and dorsal closure of fruit fly embryo development image analyzing and processing
  • Optical properties in arrays of gold trimers

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